To mark the Genomapp’s 10th anniversary we’re introducing the new Featured Condition section. The first condition featured is Ehlers-Danlos syndrome.
Ehlers-Danlos syndrome (EDS) is not a single disease but a group of 13 distinct hereditary disorders that share characteristics such as joint hyperlaxity, skin hyperextensibility, and tissue fragility. These syndromes are due to genetic changes that affect connective tissue, which provides support and structure to the entire body.
Ehlers-Danlos syndrome is caused by inherited mutations in genes that encode collagen or related proteins. These mutations affect the strength and elasticity of connective tissues. Mutations in various genes such as COL5A1, COL5A2, and COL3A1 have been identified, depending on the specific type of EDS.
Most common EDS symptoms:
- Joint Hypermobility
- Skin Hyperextensibility
- Fragile Skin
- Chronic Pain
- Fatigue
- Digestive Problems
- Dizziness and Tachycardia on Standing
- Abnormal Scarring
- Frequent Joint Dislocations
- Cardiovascular Problems
Since EDS is genetic, it can’t be prevented, but you can take steps to avoid complications and feel better day-to-day.
Living with EDS can be challenging, and support from others who understand the condition is invaluable. Among the resources and organizations related to EDS we can mention The Ehlers-Danlos Society: Global organization dedicated to research, education, and support for individuals with EDS and hypermobility spectrum disorders.
More information in Genomapp’s app. Discover what your DNA says about your predisposition to this condition.
