This report englobes conditions related to genes that play a role in methylation mechanisms, like Methylenetetrahydrofolate reductase (MTHFR), and folate and homocysteine metabolism.

Folate is a generic term for both naturally occurring folate found in foods and folic acid (synthetic form of folate). People who are unable to convert folic acid to its active forms in the body, have a build up of toxic by-products such as Homocysteine, which has been associated with many diseases.

What is Methylation?

Besides genetic variation and environmental factors, methylation mechanisms also play an important role in the cause of complex diseases. This category englobes conditions related to genes that play a role in methylation mechanisms, like key gene Methylenetetrahydrofolate reductase (MTHFR), and folate and homocysteine metabolism.

Genetic variations on these genes could cause disturbed homocysteine and folate metabolism that could impact how well your body metabolizes folate and folic acid and may be implicated in many different diseases, including congenital birth defects like congenital heart disease, cleft lip and palate, late pregnancy complications, different kinds of neurodegenerative and psychiatric diseases, osteoporosis and cancer.

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